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within a biological system. In people, the brain’s clock mechanism is located in an area of the hypothalamus known as the suprachiasmatic nucleus . The SCN is comprised of about 20,000 nerve cells. The axons of light-sensitive neurons in the retina provide information to the SCN based on the amount of light present, allowing this internal clock to be synchronized with the outside world (Klein, Moore, & Reppert, 1991; Welsh, Takahashi, & Kay, 2010) . Our sleep-wake cycle, which is linked to our environment’s natural light-dark cycle, is perhaps the most obvious Amazing teacher watch your thoughts they become words posterexample of a circadian rhythm, but we also have daily fluctuations in heart rate, blood pressure, blood sugar, and body temperature. Some circadian rhythms play a role in changes in our state of consciousness. During person-years at risk (mean follow-up, 12.6 years), 385 current drinkers developed dementia. Figure 3 shows that, after controlling for overall alcohol consumption and compared with those who had not lost consciousness during the past 12 months, losing consciousness once (HR, 2.10; 95% CI, 1.42-3.11) or more than once (HR, 2.19; 95% CI, 1.40-3.42) was associated with an increase in the dementia incidence. Similarly, compared with participants who did not report losing consciousness and were moderate drinkers,

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