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dose of cadmium and tubular and glomerular kidney effects, which may represent early signs of adverse effects. Women with diabetes seemed to be at increased risk of experiencing such early signs. In view of these data it seems plausible that at a background exposure that is common in Sweden, old women in the general population may be at risk for adverse cadmium effects and that even a modest increase in cadmium exposure due to polluted soil may lead to added risk. However, when establishing soil clean-up standards in Sweden this background exposure has been neglected . Nawrot et al. have studied the relation between mortality and cadmium body burden in Belgium. They obtained evidence that total mortality and non-cardiovascular mortality may be elevated at cadmium body burdens which can be found among the population not living on soils that are currently considered to be a health risk. Similarly there are now strong indications that the negative effects of lead on the neurophysiologic and sexual

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