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Deforestation and urban developments alter runoff and groundwater recharge patterns. Moreover, pollutants including nitrates from agricultural fertilization and acidic deposition; metals such as copper, cadmium, zinc, and lead from mining; industrial and agricultural activities; and organic pollutants from industrial and agricultural activities have increased in many of the freshwater and coastal marine ecosystems of the developed world.67 Although reduction of a number of these pollutants has been observed in a number of lakes and rivers,68 the negative consequences of these changes for aquatic ecosystems and the diversity of biota they hold are enormous. The feedback effects to human welfare argue for the necessity of management approaches that explicitly protect aquatic ecosystems for the services they provide to humans (Table 4.5). 50 years ago, the global environment now carries a number of synthetic chemicals that can interfere with human physiology, including the endocrine system, the immune system, and neurological function.10 Amazing personalized name jersey houston texans full printing shirt Additionally, heavy metal deposition in the environment is rising and will continue to increase under development scenarios implicit in meeting our normative goals. Health effects of exposure to heavy metals may be substantial, and include long-term neurological effects on intelligence and behavior. Air pollution is a critical problem of urban systems in many regions of the world, and the increase in air pollution with a rapidly urbanizing world raises serious concerns for human health and the health of crops and natural ecosystems. As described in Chapter 2, over the past several decades, there has been an emergence, resurgence, and redistribution of infectious diseases.