EXCESS WEIGHT AND WEIGHT GAIN, AND MORBIDITY AND MORTALITY. The constructed environment (urban sprawl, walkability, and so forth.) has also been implicated in weight problems risk. Rising genetic threat at 32 BMI-related loci, coupled with larger SSB consumption, resulted in an exponentially greater threat of weight problems ( Determine three ). 20 In an analogous evaluation, a genetic risk score interacted with fried meals consumption, showing that frequent consumption of fried food magnified genetic risk.